PRAC Recommends Contraindication for Zytiga and Xofigo

Drug Industry Daily
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The EMA’s Pharmacovigilance Risk Assessment Committee recommended contraindicating the use of Zytiga (abiraterone acetate) with Xofigo (radium-223 dichloride) and prednisone/prednisolone, after preliminary clinical trial results showed the combination posed an increased risk of fractures and death.

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