The European Medicines Agency said Wednesday it needs to scale back or suspend more activities, blaming Brexit for staff reductions that are disrupting its ability to function. 

The planned transfer of the agency’s headquarters from London to Amsterdam by next March has caused “significant staff loss,” EMA officials said.

Last year, the agency estimated it had around 700 employees and predicted the move from London to Amsterdam would cost about 200 jobs. But it’s now predicting more staff reductions.