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Triple Antiviral Combo Shows Promise in COVID-19 Trial

May 12, 2020
A triple antiviral combination has shown promise in a phase 2 trial of 127 patients in Hong Kong with mild to moderate COVID-19.
The researchers tested a combination of the HIV antiviral lopinavir-ritonavir, the hepatitis C treatment ribavirin and the multiple sclerosis treatment interferon beta-1, and found that the combination suppressed the virus at day seven, five days earlier than in participants given lopinavir-ritonavir alone.
The triple combination was also shown to be safe, with only minor gastrointestinal adverse events, including diarrhea and vomiting.
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