Home » Janssen Phase 3 HIV Vaccine Study Halted Due to Lack of Efficacy
Janssen Phase 3 HIV Vaccine Study Halted Due to Lack of Efficacy
Janssen has decided to discontinue the phase 3 Mosaico study evaluating the company’s investigational HIV vaccine regimen because the regimen was not effective in preventing HIV infection compared to placebo.
The study evaluated a “mosaic” vaccine based on genetic material from multiple HIV strains, which is intended to trigger a broader immune response compared with other vaccines.
The investigational vaccine regimen was administered during four visits within one year along with a mix of soluble proteins given during the third and fourth visits.
Although the study is being discontinued, “further analyses of the data are underway,” Janssen said.
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