ARROWHEAD ANNOUNCES ISSUANCE OF PATENT COVERING TARGETED THERAPEUTICS

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Arrowhead Research has announced the U.S. Patent Office has issued U.S. Patent 7,018,609, Compositions Containing Inclusion Complexes.

The patent claims cover methods of preparing new therapeutic compositions by assembling drug agents, cyclodextrin-containing polymers and compounds that provide stabilization and targeting abilities. The assembly of the new compositions occurs through the formation of inclusion complexes between the cyclodextrin-containing polymers and the stabilizing/targeting agents. These interactions do not involve the formation of strong chemical bonds and thus provide new ways of PEGylating and targeting that distinguish this technology from other patented approaches to the stabilization and targeting of small molecule, protein and nucleic acid therapeutics.