Home » ARRAY BIOPHARMA BEGINS TRIAL OF MEK INHIBITOR
ARRAY BIOPHARMA BEGINS TRIAL OF MEK INHIBITOR
Array BioPharma has announced the initiation of a Phase I clinical trial for its proprietary small molecule, ARRY-438162, a novel MEK inhibitor for the treatment of inflammatory disease.
ARRY-438162 will be evaluated in dose escalation studies in normal, healthy volunteers. ARRY-438162 was potent, selective, well-tolerated and efficacious in preclinical models of human inflammatory diseases.
MEK is a protein kinase that regulates both the biosynthesis of and response to a number of growth factors that drive uncontrolled inflammation associated with many human diseases.
KEYWORDS Drug Pipeline Alert
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