Home » ImmunoGen Announces Start of Trastuzumab-DM1 Phase II Testing
ImmunoGen Announces Start of Trastuzumab-DM1 Phase II Testing
ImmunoGen announced that Genentech has started Phase II clinical testing of trastuzumab-DM1 as a potential treatment of human epidermal growth factor receptor 2 (HER2)-expressing metastatic breast cancer.
According to Immunogen, this event triggers a $5 million milestone payment from Genentech.
Trastuzumab-DM1 comprises ImmunoGen’s cell-killing agent, DM1, linked to Genentech’s HER2-targeting antibody, trastuzumab, the companies said.
The Phase II study now underway assesses trastuzumab-DM1 in patients with HER2-expressing metastatic breast cancer that has progressed on treatment with Herceptin (trastuzumab) plus chemotherapy, the companies added.
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