MacroChem Reports Interim Data for EcoNail

November 7, 2007

Fifty-four percent of patients who completed 24 weeks of treatment in a 48-week, U.S.-based, multicenter, open-label Phase II study of MacroChem’s EcoNail, a treatment of nail fungus, showed improvement.

EcoNail is the company's patented lacquer containing the antifungal econazole and MacroChem's enhancer Sepa.

An external panel assessed photographs of 37 onychomycosis trial subjects. At week 24, 100 percent of patients had cultures that were negative for dermatophyte growth. The panel observed no signs of local irritation related to the once-daily EcoNail treatment, and 32 percent of patients demonstrated at least 25 percent improvement, MacroChem said.