FDAnews
www.fdanews.com/articles/123243-publication-details-discovery-of-allosteric-small-molecule-modulators-of-pde4

Publication Details Discovery of Allosteric Small Molecule Modulators of PDE4

December 28, 2009
Emerald BioStructures announced Monday a publication in the December 27, 2009 advance online issue of Nature Biotechnology, detailing the application of structure-based drug design to engineer new allosteric small molecule modulators of the enzyme phosphodiesterase-4 (PDE4), with reduced side effects.
Earth Times