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RegeneRx’s Dry Eye Treatment Flops in Phase 2/3

May 12, 2016

RegeneRx Biopharmaceuticals’ dry eye candidate RGN-259 missed its primary endpoints in a Phase 2/3 trial, failing to show statistically significant improvements in either total ocular discomfort or total corneal fluorescein staining.

Despite the failed results in the 317-patient trial to treat severe dry eye, the company said that the drug showed significant results in several endpoints, such as “fast-acting treatment effect” on dry eye symptoms when exposed to an adverse environment or natural environment after 28 days of dosing, the company says. No adverse events were observed.

 

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