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FDA Asks for Comments on WHO Recommendations on Drug Substances That May Lead to Dependence

February 16, 2022

The FDA is asking for public comment on recent recommendations by the World Health Organization’s Expert Committee on Drug Dependence to impose international manufacturing and distributing restrictions on certain drugs that may lead to dependence.

The list includes five new psychoactive substances, including one synthetic cannabinoid receptor antagonist (4F-MDMB-BICA), two novel synthetic opioids (brorphine and metonitazene) and two cathinones/stimulants (eutylone and benzylone).

The deadline for comments is Feb. 28. The agency said the comments will be helpful for the U.S. delegation to the upcoming March 14-18 meeting of the United Nations Commission on Narcotic Drugs in Vienna, Austria.

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