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www.fdanews.com/articles/72394-genasense-updates-phase-iii-results-in-malignant-melanoma

Genasense Updates Phase III Results in Malignant Melanoma

May 17, 2005

Genta has released long-term follow-up results from the company's Phase III trial of Genasense (oblimersen sodium) injection in patients with advanced malignant melanoma.

Earlier analyses showed that the addition of Genasense to chemotherapy yielded a statistically significant increase in overall response, complete response and time to progression.

Extended follow-up for a minimum of 24 months in all patients has revealed that patients treated with Genasense also achieved a significant increase in durable response (responses longer than six months duration) and a near-significant trend toward increased overall survival.

Lastly, the analyses showed that a blood test could be used to identify patients who were likely to derive maximal benefit from Genasense treatment.