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www.fdanews.com/articles/75393-nuvasive-launches-percutaneous-i-pas-insulated-pedicle-access-system

NUVASIVE LAUNCHES PERCUTANEOUS I-PAS INSULATED PEDICLE ACCESS SYSTEM

August 15, 2005

NuVasive, Inc. (Nasdaq: NUVA), a medical device company focused on developing products for minimally disruptive surgical treatments for the spine, announced today the launch of the Insulated Pedicle Access System, or I-PAS(TM), a surgical instrument used to determine the safe percutaneous approach pathway of a pedicle screw prior to its implantation. I-PAS is designed to be used in conjunction with the Company's NeuroVision(R) nerve avoidance software to dynamically test the percutaneous approach of a pedicle screw prior to its implantation into the vertebral body.

Reuters (http://today.reuters.com/stocks/QuoteCompanyNewsArticle.aspx?view=PR&symbol=NUVA&storyID=262363%2B11-Aug-2005%2BPRN)