www.fdanews.com/articles/75825-nexmed-releases-results-of-phase-i-fungus-study
NEXMED RELEASES RESULTS OF PHASE I FUNGUS STUDY
August 26, 2005
NexMed has reported that an early study showed its topical nail fungus treatment
left substantially less drug in the bloodstream than the leading oral medicine,
potentially making it a safer therapy.
The company's experimental NM100060 treatment uses a proprietary technology
to boost the skin's drug absorption. It contains less than 1 percent of the
oral dose of terbinafine, the active ingredient in Novartis AG's Lamisil tablet.
The NexMed drug showed peak blood plasma levels about 2,500 times less than
those of a single Lamisil tablet, and were comparable with the blood levels
of an athlete's foot cream using the same active ingredient.