FDAnews
www.fdanews.com/articles/80726-study-shows-cancer-drug-success

STUDY SHOWS CANCER DRUG SUCCESS

September 7, 2005

Geron reported that one of its drugs showed efficacy against liver and lung cancer in animal models. GRN163L, a cancer drug that targets the enzyme telomerase, inhibited tumor growth associated with lung cancer in mouse models, according to a study that appears in the current online publication of the journal Hepatology, conducted by researchers at Geron and Hannover Medical School in Germany.

Telomerase is an enzyme that helps protect cells, thwarting attempts to kill off cancer cells. The drug is currently in clinical testing in a Phase I/II trial in patients with chronic lymphocytic leukemia.