CYTORI PRESENTS PRECLINICAL RESULTS OF CARDIAC FUNCTION STUDY

Cytori Therapeutics has presented results demonstrating that adipose stem and regenerative cells improved cardiac function following a severe heart attack in an animal study using pigs. This is the first preclinical study in which the injected cells were autologous (meaning they came from the animals' own tissue), were not cultured, and were harvested and administered on the day of the heart attack. The results of the study, conducted in collaboration with Tulane University, were presented at the Cardiovascular Research Foundation's 17th Annual Transcatheter Cardiovascular Therapeutics Scientific Symposium in Washington, D.C.

In this randomized study, 17 animals received either injections of their own adipose stem and regenerative cells (treated) or a saline injection (control) via catheter into the artery at the site of the heart attack. After eight weeks, there was a statistically significant reduction in the perfusion defect, which is the area of the heart deprived of oxygen as a result of the infarct. A corresponding benefit was observed by the improvement in ejection fraction, a common measure of the heart's pumping efficiency.