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www.fdanews.com/articles/82523-aphton-announces-closing-of-commercialization-and-manufacturing-agreements-for-ign311-with-celltrion

APHTON ANNOUNCES CLOSING OF COMMERCIALIZATION AND MANUFACTURING AGREEMENTS FOR IGN311 WITH CELLTRION

November 17, 2005

Aphton Corporation (NASDAQ:APHT) announced the formal completion of two agreements with Celltrion, Inc., South Korea for the licensing and commercialization and the product development and manufacturing of Aphton's clinical product candidate IGN311. IGN311, a humanized monoclonal antibody targeting the Lewis Y antigen, is being developed by Aphton's wholly-owned subsidiary, Igeneon AG, as a potential new therapy for the treatment of cancer. Lewis Y is a tumor-related antigen that is expressed in up to 90% of all epithelial cancers, including breast, colon, gastric, and pancreatic cancers.

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