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www.fdanews.com/articles/82639-immutep-begins-phase-i-trial-in-renal-cell-cancer

IMMUTEP BEGINS PHASE I TRIAL IN RENAL CELL CANCER

November 22, 2005

Immutep has initiated a Phase I clinical trial of its lead product ImmuFact IMP321 in metastatic renal cell carcinoma. This is the company's first clinical trial targeting cancer. ImmuFact IMP321 is a potent natural human T-cell immunostimulatory factor designed to amplify the T-cell immune response through activation of dendritic cells and more efficient antigen presentation to T-cells.

The single-center, open-label study is designed to assess the safety and tolerability of six subcutaneous injections of IMP321 at two-week intervals. Additional patients may be recruited into the trial to provide more data on safety or response rates.