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ORGANON ENTERS INTO DISTRIBUTION AGREEMENT FOR ANZEMET

December 5, 2005

Today Organon USA Inc., a business unit of Akzo Nobel NV, announced that they have entered into a distribution agreement for Anzemet(R) Injection (dolasetron mesylate injection) with Aventis Pharmaceuticals Inc., a member of the sanofi-aventis Group, which will be become effective January 1, 2006. Organon USA Inc. will be responsible for the marketing, sales, and managed markets activities including pricing and contracting as well as recording sales for Anzemet(R) Injection for use in the prevention and treatment of postoperative nausea and/or vomiting (PONV).

PR Newswire (http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-05-2005/0004227589&EDATE=)