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AFFYMAX ANNOUNCES RESULTS OF HEMATIDE TRIAL

December 5, 2005

Affymax has announced results from a Phase II clinical trial of Hematide in patients with anemia due to chronic kidney disease (CKD). Hematide is a novel peptide-based drug candidate designed to stimulate the production of red blood cells.

The trial is a randomized, double-blind, placebo-controlled, dose-escalation study evaluating a single intravenous injection of Hematide administered to patients with CKD. The study found that Hematide was well-tolerated and demonstrated potent and sustained erythropoietic activity of the same magnitude as that observed in healthy volunteers.