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AMGEN ANNOUNCES $5 BILLION STOCK REPURCHASE PLAN

December 7, 2005

Amgen (NASDAQ:AMGN), the world's largest biotechnology company, today announced that its board of directors has authorized additional repurchases of up to $5 billion in Amgen common stock. The company currently has $2 billion remaining under its previous stock repurchase program. This new authorization reflects Amgen's confidence in its long-term prospects.

Genetic Engineering News (http://www.genengnews.com/news/bnitem.aspx?name=1121346XSL_NEWSML_TO_NEWSML_WEB.xml)