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DURECT CORPORATION ANNOUNCES ANTICIPATED DEVELOPMENT PROGRAM MILESTONES FOR FISCAL YEAR 2006

February 8, 2006

Durect Corporation today announced its intended development milestones for fiscal year 2006. "These announced milestones are intended to assist the investment community to track our progress throughout the coming year," said James E. Brown, President and CEO of Durect. "Durect will continue to drive forward our development programs in 2006. In addition, we intend to build-out our commercial specialty pharmaceuticals infrastructure and continue to forge commercial alliances for our products and technologies that build lasting value for our shareholders."
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