FDAnews
www.fdanews.com/articles/84473-preventing-the-unwanted-side-effects-of-autoimmune-disease-therapy

PREVENTING THE UNWANTED SIDE EFFECTS OF AUTOIMMUNE DISEASE THERAPY

February 10, 2006

Treatment for autoimmune and inflammatory disorders such as multiple sclerosis often includes blocking a special cell surface attachment molecule known as alpha4 integrin to prevent migration of white blood cells (WBCs). However, this therapy can cause adverse side effects, such as impaired immunity and hematopoiesis [the process of development of new WBCs in the thymus (T cells) and bone marrow (B cells)].

Medical News Today (http://www.medicalnewstoday.com/medicalnews.php?newsid=37520)

(http://www.bloomberg.com/apps/news?pid=10000102&sid=aYW4iYmkPTMc&refer=uk)