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ENTREMED REPORTS FOURTH QUARTER AND YEAR-END 2005 FINANCIAL RESULTS

March 7, 2006

EntreMed, Inc. a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, today reported results for the three months and twelve months ended December 31, 2005. Revenues for the fourth quarter ended December 31, 2005 were $4.1 million versus $134,000 for the comparable period in 2004. The Company reported a net loss of ($2.4 million), or ($.05) per share for the three months ended December 31, 2005. This compares with a net loss of ($511,000), or ($0.02) per share for the fourth quarter 2004.
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