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ACADIA'S ACP-103 HAS POSITIVE PHASE II RESULTS

March 27, 2006

Acadia Pharmaceuticals has reported postitive data from a Phase II clinical trial of its drug candidate ACP-103 in patients with Parkinson's disease suffering from treatment-induced psychosis.

In the multicenter, double-blind, placebo-controlled, 60-patient trial, the agent met the primary endpoint of motoric tolerability as measured by the Unified Parkinson's Disease Rating Scale, by demonstrating that it did not worsen motor function. The study also evaluated secondary endpoints of antipsychotic efficacy using three different rating scales, and ACP-103 demonstrated antipsychotic effects on two of these measures.