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www.fdanews.com/articles/86100-acadia-reports-positive-results-from-trial-of-acp-103

ACADIA REPORTS POSITIVE RESULTS FROM TRIAL OF ACP-103

April 17, 2006

Acadia Pharmaceuticals has reported the results from a Phase II clinical trial of ACP-103 in patients with Parkinson's disease suffering from treatment-induced psychosis.

ACP-103 met the primary endpoint of the clinical trial -- motoric tolerability as measured by the Unified Parkinson's Disease Rating Scale -- by demonstrating that it did not worsen motor function in Parkinson's patients. The trial also evaluated secondary endpoints of antipsychotic efficacy using three different rating scales, and ACP-103 demonstrated antipsychotic effects on two of these rating scales. The drug was safe and well-tolerated in patients with Parkinson's disease.