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THERAPEUTICS REPORTS FIRST QUARTER 2006

May 2, 2006

Sirna Therapeutics, Inc. RNAI today reported financial results for the first quarter ended March 31, 2006. For the quarter ended March 31, 2006, Sirna reported a net loss of $8.0 million, or $0.13 per share, compared to a net loss of $8.0 million, or $0.19 per share, for the same period in 2005. MSN Money (http://news.moneycentral.msn.com/provider/providerarticle.asp?feed=PR&Date=20060502&ID=5686013)