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www.fdanews.com/articles/87168-neopharm-begins-patient-enrollment-in-le-sn38-trial

NEOPHARM BEGINS PATIENT ENROLLMENT IN LE-SN38 TRIAL

May 30, 2006

NeoPharm has begun patient enrollment in a multicenter Phase II clinical trial of LE-SN38 for the treatment of patients with metastatic colorectal cancer. The company noted that this trial will seek to enroll up to 54 patients.

The National Cancer Institute-sponsored Cancer and Leukemia Group B is conducting this trial. The company said that the primary endpoint of the trial is overall tumor response rate following treatment with LE-SN38 as a second-line treatment in patients with metastatic colorectal cancer.