Moderna Prepping Single-Dose COVID-19 and Flu Booster
Moderna is working on a new booster vaccine, mRNA-1073, that combines the drugmaker’s COVID-19 shot with its experimental flu vaccine in a single dose.
The combination vaccine is meant to target both the SARS-CoV-2 spike protein that the coronaviruses uses to enter human cells and the influenza hemagglutinin glycoprotein that plays a key role in influenza infections.
Moderna said that “robust antibody responses” have been observed in a mid-stage study assessing a booster dose of its existing COVID-19 vaccine, mRNA-1273.
The company has also fully enrolled a phase 1 study to evaluate its next-generation COVID-19 vaccine, mRNA-1283.