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Home » Adaptive Trials: Consent Can Be Tricky, Clarify Expectations vs. Experience
Adaptive Trials: Consent Can Be Tricky, Clarify Expectations vs. Experience
September 12, 2012
Adaptive clinical trials can allow sites to enroll small numbers of patients and end a trial early if the desired outcome appears unlikely, but investigators must take care to ensure that study participants understand they are consenting to a moving protocol and that patients who enroll later may see more benefits than early enrollees, a pair of recent articles in Journal of the American Medical Association (JAMA) suggests.